For Patients & Visitors

Doctor Details

2024/01/25
Find a Doctor
Doctor Detail

Dr Tan Lip Kun

Photo of Dr Tan Lip Kun

Designations:

  • Senior Consultant, Division of Haematology, Department of Haematology-Oncology, National University Cancer Institute, Singapore
  • Senior Consultant, Haematology Division, Department of Laboratory Medicine, National University Hospital
  • Assistant Professor, Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore

Qualifications:

MBChB, FRCP, FRCPath

Specialties/Sub-specialties:

Haematology

Clinical Disciplines/Programmes:

Laboratory Medicine

Special Interests:

Stem Cell Transplant, Cell Therapy, Haemtologic Malignancies, Transfusion Medicine

Biosketch

Dr Tan Lip Kun is a Senior Consultant Haematologist in the Department of Laboratory Medicine, NUHS> She graduated from Leicester Medical School, UK, in 1989. She was trained in both internal medicine and in Haematology. Dr. Tan has extensive experience in both laboratory and clinical haematology, with particular interests in : Acute Leukaemias, Lymphoproliferative diseases, Haematopoietic Stem Cell Transplantation and Transfusion Medicine.  Dr Tan was previously the Program Director for the NUHS Adult and Paediatric Haematopoietic Stem Cell Transplant Programme, a FACT-accredited centre. She is currently the Medical Director of the Processing Facility, Stem Cell Laboratory and Collection Facility, Apheresis Unit, NCIS. She is the Medical Director of the Blood Transfusion Services. She actively participates in both undergraduate teaching at Yong Loo Lin School of Medicine, NUS and postgraduate teaching in Haematology. Dr  Tan is a member of the Clinical Ethics Committee and a member of the Blood Usage Committee at NUHS. At the National level, Dr Tan held the position of the Protem Executive Director and was tasked to set up the Advanced Cell Therapy and Research Institute, Singapore (ACTRIS), a national cell and gene therapy program and GMP facility. She now serves as a member of the Clinical Services Strategy Committee for Cell Therapy. She is also a member of the Product Vigilance Advisory Committee of HSA.Dr Tan's interest is in stem cell transplant, cell therapy, haematologic malignancies and transfusion medicine. 

Awards

  • 2024 - NUHS - Long Service Award
  • 2023 - National Day Awards - Long Service Medal

Journals & Publications

  1. Role of Conventional Karyotyping in Multiple Myeloma in the Era of Modern Treatment and FISH Analysis. Soekojo CY, Wang GM, Chen Y, Casan J, Wolyncewicz G, Lin A, Poon LM, de Mel S, Koh LP, Tan LK, Ooi MG, Nagarajan C, Liu Y, Lai YY, Huang XJ, Spencer A, Gopalakrishnan SK, Lu J, Chng WJ.Clin Lymphoma Myeloma Leuk. 2019 Aug;19(8):e470-e477. doi: 10.1016/j.clml.2019.04.011. Epub 2019 Apr 28.
  2. Phase I Trial of Expanded, Activated Autologous NK-cell Infusions with Trastuzumab in Patients with HER2-positive Cancers. Lee SC, Shimasaki N, Lim JSJ, Wong A, Yadav K, Yong WP, Tan LK, Koh LP, Poon MLM, Tan SH, Ow SGW, Bharwani L, Yap YS, Foo MZQ, Coustan-Smith E, Sundar R, Tan HL, Chong WQ, Kumarakulasinghe NB, Lieow JLM, Koe PJX, Goh BC, Campana D.Clin Cancer Res. 2020 Sep 1;26(17):4494-4502. doi: 10.1158/1078-0432.CCR-20-0768. Epub 2020 Jun 10.
  3. Application of an ex-vivo drug sensitivity platform towards achieving complete remission in a refractory T-cell lymphoma. de Mel S, Rashid MBM, Zhang XY, Goh J, Lee CT, Poon LM, Chan EHL, Liu X, Chng WJ, Chee YL, Lee J, Yuen YC, Lim JQ, Chia BKH, Laurensia Y, Huang D, Pang WL, Cheah DMZ, Wong EKY, Ong CK, Tang T, Lim ST, Ng SB, Tan SY, Loi HY, Tan LK, Chow EK, Jeyasekharan AD.Blood Cancer J. 2020 Jan 27;10(1):9. doi: 10.1038/s41408-020-0276-7.
  4. Rapid production of clinical-grade SARS-CoV-2 specific T cells.Leung W, Soh TG, Linn YC, Low JG, Loh J, Chan M, Chng WJ, Koh LP, Poon ML, Ng KP, Kuick CH, Tan TT, Tan LK, Seng MS.Adv Cell Gene Ther. 2020 Oct;3(4):e101. doi: 10.1002/acg2.101. Epub 2020 Jul 31.
  5. Effective Killing of Acute Myeloid Leukemia by TIM-3 Targeted Chimeric Antigen Receptor T Cells. Lee WS, Ye Z, Cheung AMS, Goh YPS, Oh HLJ, Rajarethinam R, Yeo SP, Soh MK, Chan EHL, Tan LK, Tan SY, Chuah C, Chng WJ, Connolly JE, Wang CI.Mol Cancer Ther. 2021 Sep;20(9):1702-1712. doi: 10.1158/1535-7163.MCT-20-0155. Epub 2021 Jun 22.
  6. Dendritic cell therapy with CD137L-DC-EBV-VAX in locally recurrent or metastatic nasopharyngeal carcinoma is safe and confers clinical benefit. Nickles E, Dharmadhikari B, Yating L, Walsh RJ, Koh LP, Poon M, Tan LK, Wang LZ, Ang Y, Asokumaran Y, Chong WQ, Huang Y, Loh KS, Tay J, Soo R, Koh M, Ho LP, Chan M, Niam M, Soh M, Luah YH, Lim CM, Kaliaperumal N, Au VB, Talib NBSN, Sng R, Connolly JE, Goh BC, Schwarz H.Cancer Immunol Immunother. 2022 Jun;71(6):1531-1543. doi: 10.1007/s00262-021-03075-3. Epub 2021 Oct 18.
  7. Phase I study of expanded natural killer cells in combination with cetuximab for recurrent/metastatic nasopharyngeal carcinoma. Lim CM, Liou A, Poon M, Koh LP, Tan LK, Loh KS, Petersson BF, Ting E, Campana D, Goh BC, Shimasaki N.Cancer Immunol Immunother.2022 Sep;71(9):2277-2286.doi:10.1007/s00262-022-03158-9.Epub 2022Jan 30.
  8. An ex vivo platform to guide drug combination treatment in relapsed/refractory lymphoma. Goh J, De Mel S, Hoppe MM, Mohd Abdul Rashid MB, Zhang XY, Jaynes P, Ka Yan Ng E, Rahmat NDB, Jayalakshmi, Liu CX, Poon L, Chan E, Lee J, Chee YL, Koh LP, Tan LK, Soh TG, Yuen YC, Loi HY, Ng SB, Goh X, Eu D, Loh S, Ng S, Tan D, Cheah DMZ, Pang WL, Huang D, Ong SY, Nagarajan C, Chan JY, Ha JCH, Khoo LP, Somasundaram N, Tang T, Ong CK, Chng WJ, Lim ST, Chow EK, Jeyasekharan AD.Sci Transl Med. 2022 Oct 19;14(667):eabn7824. doi: 10.1126/scitranslmed.abn 7824. Epub 2022 Oct 19.
  9. Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis. Guo M, Chan THM, Zhou Q, An O, Li Y, Song Y, Tan ZH, Ng VHE, Peramangalam PS, Tan ZQ, Cao X, Iwanaga E, Matsuoka M, Ooi MGM, Jen WY, Koh LP, Chan E, Tan LK, Goh Y, Wang W, Koh BTH, Chun CM, Fullwood MJ, Chng WJ, Osato M, Pulikkan JA, Yang H, Chen L, Tenen DG.Blood. 2023 Jun 22;141(25):3078-3090. doi: 10.1182/blood.2022015830.
  10. Fratricide-resistant CD7-CAR T cells in T-ALL.. Oh BLZ, Shimasaki N, Coustan-Smith E, Chan E, Poon L, Lee SHR, Yeap F, Tan LK, Chai LYA, Le Bert N, Tan N, Bertoletti A, Chen SP, Del Bufalo F, Becilli M, Locatelli F, Yeoh AEJ, Campana D. Nat Med. 2024 Dec;30(12): 3687-3696.doi:10.1038/s41591-024-03228-8. Epub 2024 Sep 3.PMID: 39227445

Professional Memberships

  • American Society for Blood & Marrow Transplantation
  • European Group for Blood & Marrow Transplantation
  • Royal College of Pathologists, United Kingdom
  • Singapore Society of Haematology

2024/12/30
Last updated on
Best viewed with Chrome 79.0, Edge 112.0, Firefox 61.0, Safari 11
National University Health System
  • National University Hospital
  • Ng Teng Fong General Hospital
  • Alexandra Hospital
  • Jurong Community Hospital
  • National University Polyclinics
  • Jurong Medical Centre
  • National University Cancer Institute, Singapore
  • National University Heart Centre, Singapore
  • National University Centre for Oral Health, Singapore
  • NUHS Diagnostics
  • NUHS Pharmacy
  • Yong Loo Lin School of Medicine
  • Faculty of Dentistry
  • Saw Swee Hock School of Public Health
Back to Top