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A/Prof Tan Soo Yong

Designations:
  • Head & Senior Consultant, Department of Pathology, National University Hospital
  • Associate Professor, Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore
  • Group Chief, Pathology, National University Health System
Qualifications:
MBBS, DipRCPath, MRCPath, FRCPath, DMJ(path), DPhil(Oxon)
Specialties:
Pathology
Special Interests:
​Pathological diagnosis of haematolymphoid diseases

Biosketch

Dr Tan Soo Yong is Group Chief of Pathology, National University Health System, Associate Professor and Head of the Department of Pathology, National University of Singapore. Apart from his concurrent appointments as Research Director, Advanced Molecular Pathology Laboratory in IMCB, A*STAR, Visiting Consultant to National Skin Centre and Advisor to the Ministry of Health, he was Chairman, National Pathology Clinical Governance and Performance Workgroup, Chief Examiner in Pathology and Chair of the Residency Advisory Committee for Pathology.

He obtained his medical qualifications from the National University of Singapore and qualified in both forensic and histopathology. He is a Fellow of the Royal College of Pathologists (UK) and a Diplomate of the Society of Apothecaries of London. Dr Tan obtained his PhD from Oxford. He is a member of the International Lymphoma Study Group (ILSG) and a contributing author to the WHO Classifications of haematolymphoid neoplasms, tumours of the skin and tumours of the digestive tract. Dr Tan sits on the Editorial Board of the Journal of Hematopathology and is Chair of the Biobanking Subcommittee, Asian Network of Research Resource Centers. 

An educator at heart, he was the founding Course Director at Duke-NUS Graduate Medical School and had Visiting Professorships at University Malaya (Malaysia), Guangdong Academy of Medical Sciences (China) and Universitas Padjadjaran (Indonesia). For many years, Dr Tan was also the International Advisor (West Pacific) of the Royal College of Pathologists and initiated a postgraduate pathology training program in Myanmar. His current research interests include the cellular origins of intestinal T-cell lymphoma and the use of novel technologies in lymphoma diagnosis.

Awards

  • 2023: National Day Public Administration Medal (Bronze) Pingat Pentadbiran Awam (Gangsa)
  • 2022: National Day Long Service Medal Pingat Bakti Setia
  • 2021: Distinguished Senior Physician Award
  • 2018: MOH 10-years Long Service Award
  • 2013: Duke-NUS Dean’s Excellence Award
  • 2011: Duke-NUS Pioneer Award

Journals & Publications

  1. Laurensia Y, Huang D, Pang WL, et. Al. Application of an ex-vivo drug sensitivity platform towards achieving complete remission in a refractory T-cell lymphoma. Blood Cancer J. 2020 Jan 27;10(1):9.
  2. Susan SH, Ng SB, Wang S, et al. Diagnostic approach to T- and NK-cell lymphoproliferative disorders in the gastrointestinal tract. Semin Diagn Pathol. 2021 Jul;38(4):21-30. 
  3. Lee WS, Ye Z, Cheung AMS, et al. Effective Killing of Acute Myeloid Leukemia by TIM-3 Targeted Chimeric Antigen Receptor T Cells. Mol Cancer Ther. 2021 Sep;20(9):1702-1712. 
  4. Oon ML, Lim JQ, Lee B, et. Al. T-Cell Lymphoma Clonality by Copy Number Variation Analysis of T-Cell Receptor Genes. Cancers (Basel). 2021 Jan 19;13(2):340. 
  5. Hue SS, Ng SB, Wang S, et al. Cellular Origins and Pathogenesis of Gastrointestinal NK- and T-Cell Lymphoproliferative Disorders. Cancers (Basel). 2022 May 18;14(10):2483. 
  6. Wai CMM, Chen S, Phyu T, et al. Immune pathway upregulation and lower genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS. Haematologica. 2022 Jan 13. 
  7. Amanda S, Tan TK, Ong JZL, et. Al. IRF4 drives clonal evolution and lineage choice in a zebrafish model of T-cell lymphoma. Nat Commun. 2022 May 3;13(1):2420. 
  8. Ting CY, Tan SY, Gan GG, et al. Downregulation of hsa-miR-548d-3p and overexpression of HOXA9 in diffuse large B-cell lymphoma patients and the risk of R-CHOP chemotherapy resistance and disease progression. Int J Lab Hematol. 2022 Oct;44(5):907-917. 
  9. Hue SS, Jin Y, Cheng H, et al. Tissue-Specific microRNA Expression Profiling to Derive Novel Biomarkers for the Diagnosis and Subtyping of Small B-Cell Lymphomas. Cancers (Basel). 2023 Jan 10;15(2):453. 
  10. Ran XB, Ding LW, Sun QY, et al. Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy. Cancer Res. 2023 Mar 15;83(6):922-938.

Professional Memberships

  • International Lymphoma Study Group
  • Asian Network of Research Resource Centres
  • Royal College of Pathologists
  • Society of Apothecaries of London